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Home / Mass Tort / Depo-Provera Lawsuit
A Depo-Provera lawsuit may be an option if you were diagnosed with a meningioma after years of the shot. You went in every three months. It was easy, it worked, and nobody mentioned brain tumors. Then came the headaches, or the vision changes, or a scan you were not expecting.
This page explains what is in the injection, why it has been linked to meningiomas, what treatment involves, where the settlement stands, and what you can do now.
Received the Depo-Provera shot?
About 2 minutes · free · private
Eligibility
These claims are about one specific injury: a meningioma diagnosed after repeated Depo-Provera injections. These are the guidelines participating law firms use when they review a claim.
Depo-Provera, Depo-Provera CI, Depo-SubQ Provera 104, or a generic medroxyprogesterone injection. The generics count.
The research points to prolonged use. Most claims involve several years of injections, every twelve weeks.
A tumor of the membranes around the brain or spinal cord. Confirmed by MRI or CT and documented in your records.
Craniotomy, gamma knife or ongoing monitoring. Treatment records show how serious it was and strengthen a claim.
Very common. Clinic and pharmacy records can be requested with your authorization. Not having paperwork is not a reason to skip the review.
Family members and estate representatives may be able to bring a claim. That deadline usually runs from the date of death.
Only ever knew it as “the Depo shot”?
Most women do. Nobody reads the vial. Clinic and pharmacy records show what you were given and when, and a firm can pull them for you. For official background, see MedlinePlus drug information on the Depo-Provera injection (medroxyprogesterone).
Meeting these guidelines does not mean you have a valid claim. It means a participating law firm is likely to review it. That firm decides on its own whether to take your case. Some claims are turned down, and some recover nothing. Direct2Attorney cannot judge the legal merits of your case, give legal advice, or file anything for you.
Before you decide
Many women with a real diagnosis never ask. Here are the usual reasons, and what is true.
What holds people back
Most meningiomas are not cancer.
What is true
A meningioma presses on the brain as it grows, and treatment often means brain surgery. These claims are about meningiomas, cancerous or not.
What holds people back
Many women got the shot at a clinic years ago.
What is true
Clinic and pharmacy records show what you were given and when. A firm can request them with your authorization.
What holds people back
Headlines make it sound like everyone is covered.
What is true
The federal program is for eligible plaintiffs, and the court has set rules about who can join. A firm should tell you plainly where a new claim would stand.
What holds people back
Some women fear a claim will change their birth control.
What is true
Do not stop your injections because of this page. Talk to your clinic about your options.
About the shot
Do not stop your injections because of this page. Depo-Provera is contraception. If you miss an injection, you can become pregnant. Stopping without a plan is a real risk, and nothing here is medical advice. If this page worries you, call the clinic or doctor who gives you the shot and ask about your options. There are other methods, and they can help you switch safely. That is a medical conversation, and it has nothing to do with any legal question.
Depo-Provera is an injection of medroxyprogesterone acetate. One shot every twelve weeks prevents pregnancy. For millions of women, it has been the simplest option available: nothing daily to remember, nothing to hide, nothing to explain.
A meningioma is a tumor that grows in the membranes covering the brain and spinal cord. Most are not cancerous. That does not make them harmless. As one grows, it presses on the brain, and treatment often means brain surgery.
Meningiomas carry hormone receptors. That is why researchers looked at long-term hormone injections in the first place. In 2024 a large French study in the BMJ reported the finding at the heart of these cases. Women using medroxyprogesterone for a year or more had roughly 5.5 times the risk of needing surgery for an intracranial meningioma. A 2025 study in JAMA Neurology also found an increased risk, at a lower figure of about 2.4 times.
How the link is said to work
A strong hormone, every 12 weeks
The shot delivers medroxyprogesterone acetate.
Meningiomas respond to hormones
These tumors carry hormone receptors.
Long use, higher risk
Studies found more meningiomas after a year or more of use.
For years the U.S. label carried no meningioma warning at all. Labels in several other countries did. Women in the United States were not given the same information.
Pfizer argues federal preemption: that it asked the FDA to add a meningioma warning in 2024, the FDA refused, and it therefore cannot be blamed for a warning it was not permitted to give.
| Product named in claims | What to know |
|---|---|
| Depo-Provera | The brand-name birth control shot, given every twelve weeks |
| Depo-Provera CI | Contraceptive injection version of the same drug |
| Depo-SubQ Provera 104 | A lower-dose version injected under the skin |
| Generic medroxyprogesterone | Generic versions of the injection count too |
Product and company names are used only to identify the products at issue. Direct2Attorney is not affiliated with, endorsed by, or sponsored by Pfizer, the FDA, or any court.
The medical side, in plain words
Meningiomas grow slowly, and the signs are easy to explain away. Here is what is happening, in plain words.
The tumor starts in the thin layers that cover the brain and spinal cord, not in the brain itself.
Even a benign tumor takes up space. Pressure on nearby nerves causes the symptoms.
Meningiomas carry hormone receptors, which is why long-term hormone shots were studied.
Many meningiomas are found on a scan done for something else.
Others may notice first
Changes in memory or personality are often noticed by family before you notice them yourself. If you have had the Depo shot for years and any of this sounds familiar, see a doctor and say so.
Treatment
Treatment depends on the size and place of the tumor. Each step also leaves a record, and those records later show what the tumor cost you.
General information only, not medical advice. Your care team decides your treatment. Do not stop your injections without a plan from your clinic.
Finding it
Imaging confirms the tumor and shows its size and location.
Small tumors
Regular scans to see whether it grows. Some never need surgery.
Surgery
The surgeon opens the skull to remove the tumor. Recovery can take months.
Radiation
Focused radiation to shrink or stop the tumor, alone or after surgery.
Side effects
Anti-seizure medicine, therapy and rehabilitation for lasting effects.
Hormones
The new U.S. label tells doctors to stop the drug if a meningioma is diagnosed.
Quick self-check
If you can say yes to most of these, it is worth asking for a free review.
Did you receive the Depo-Provera shot or a generic version?
Did you get it for a year or longer?
Were you diagnosed with a meningioma on an MRI or CT scan?
Did you need surgery, radiation or ongoing monitoring?
Requirements
You do not need any of this to start. A firm collects it for you. But every claim is built on these four things.
Proof of use
Clinic or pharmacy records of the injections.
Proof of the tumor
Imaging or pathology confirming a meningioma.
The right timing
Diagnosis after prolonged use.
Filed in time
Each state sets its own deadline.
Case status
Federal cases are consolidated as MDL 3140 before Judge M. Casey Rodgers in the Northern District of Florida. A settlement program is underway for eligible plaintiffs with pending federal cases.
Almost nothing about the money is public
The financial terms have not been published in the court orders we reviewed. No one can tell you what a Depo-Provera claim will pay. Cases in state court, mostly in New York and Delaware, are not part of the federal agreement.
BMJ study published
A large French study links a year or more of medroxyprogesterone to about 5.5 times the risk of meningioma surgery.
New U.S. warning label
The FDA approves a label warning of meningioma risk.
Record month and a deal in principle
1,739 new cases were filed in June, the most in any month. On June 15, 2026, the court confirmed that Pfizer and plaintiffs’ leadership had reached a global agreement in principle, and it vacated the December 2026 trial deadlines.
Settlement administrator appointed
The court appointed BrownGreer PLC to run eligibility reviews and the claims process.
Rules for the settlement program
Case Management Order 14 set a registration deadline of November 30, 2026, and strict proof and expert-report deadlines for plaintiffs who do not settle.
6,412 cases pending
As of October 1, 2026. Registration in the settlement program closes November 30, 2026. No payment has been made to anyone yet.
New claims may sit outside the settlement. Under the court’s August 10, 2026 order, a person filing now can join the settlement program only if they had signed with a lawyer by June 11, 2026 and are otherwise eligible. Others proceed as litigating plaintiffs, who must produce proof of use, proof of the tumor, medical records and expert reports within 90 days or risk dismissal. A participating firm should explain where your claim would stand before you decide anything.
The honest question
The agreement in principle arrived unusually early: before any ruling on Pfizer’s preemption motion, before the causation ruling, and before a single trial. That is rare. It suggests both sides preferred certainty to the risk of those rulings. It also means nothing has been tested in court.
The settlement covers eligible plaintiffs with cases already pending. The court has now set out who may join and when. For most people signing with a lawyer today, a claim would likely go forward as a regular lawsuit rather than through the settlement program.
Some firms have stopped accepting new Depo claims. Others are still reviewing them. Anyone who tells you a new claim is guaranteed a place in this settlement is guessing. A firm should give you a straight answer about where a new case would stand, and that answer costs nothing.
Who the settlement program is for
Compensation
If a claim succeeds, compensation is meant to cover what a brain tumor has cost you: the treatment, the time, and what did not come back afterward.
No one can tell you what your claim is worth, and no one can promise you will recover anything at all. Past results do not guarantee or predict a similar outcome in any future case.
The process
You do not need records, addresses or dates ready to start. Tell us what you remember and the firm does the rest.
Fill out the short form or call. Roughly how many years you had the shot, and when you were diagnosed. No cost, no obligation.
A participating firm should tell you plainly where a new claim would stand. If your case would sit outside the settlement, you should hear that before you decide anything.
You sign an authorization. The firm requests clinic and pharmacy records showing the injections, plus imaging, pathology and surgical records for the tumor.
Your Depo-Provera lawsuit is filed in the MDL or an appropriate state court. Your firm keeps you updated. You never have to accept an offer you do not want.
READY WHEN YOU ARE
Step 1 takes about two minutes.
Why people use us
No upfront fees
The review is free. Participating firms work on contingency, so a fee is owed only out of a recovery. No recovery, no attorney fee.
Firms still taking claims
Some firms stopped accepting Depo cases when the settlement was announced. We connect you with ones still reviewing them.
We help find the records
Most women only ever knew it as the Depo shot. Clinic and pharmacy records fill that gap, and a firm can request them.
Private and confidential
Contraception and medical history are personal. Your information is encrypted and handled according to our Privacy Policy.
What Direct2Attorney is
A legal marketing and referral service. We check whether your situation matches what participating law firms are looking for, and connect you with one of them if it does.
What Direct2Attorney is not
We are not a law firm. We cannot give you legal advice, represent you, or file anything on your behalf. Only a law firm you sign with can do that.
Firms are reviewing Depo-Provera claims
Tell us what happened. If your situation meets the screening criteria it may be referred to a participating law firm for an independent review. No cost, no obligation, and a straight answer either way, including if the answer is no.
What happens after you ask
We check your answers
Usually the same business day
A participating firm may call you
At the time you choose
You decide what comes next
No cost and no obligation, ever
Questions
Still have a question? Ask it on the call. The review is free, and there is no obligation.
Start my free review →A mass tort claim generally requires that you used a specific product, took a specific drug, or were exposed to a specific substance named in the litigation, and were later diagnosed with a condition that research or the litigation links to that exposure, within the relevant time window.
No. A free case review is free to you. Participating law firms handling mass torts typically work on a contingency basis, meaning legal fees are generally paid only if there is a recovery. Ask the firm to confirm its fee terms in writing.
Filing deadlines (statutes of limitations) vary by state and by litigation, and they can be shorter than people expect. That is why timing is one of the first things a participating firm checks — it is best not to wait to start a review.
Mass tort cases are grouped for efficiency because many people were harmed by the same product or exposure, but each person keeps an individual claim and an individual compensation outcome, unlike a class action.
It helps to have any medical records, prescriptions, diagnosis dates, receipts, or employment history that show your use, exposure, and diagnosis, though you do not need everything gathered before starting a free review.
Yes, for eligible plaintiffs with cases pending in the federal MDL. On June 15, 2026 the court confirmed that Pfizer and plaintiffs’ leadership had reached a global agreement in principle. In August 2026 the court appointed BrownGreer PLC as settlement administrator and set a registration deadline of November 30, 2026. The amount has not been published in the court orders we reviewed, and no payment had been made as of October 3, 2026.
Possibly, but probably not as part of the settlement. Under the court’s August 10, 2026 order, people filing now can join the settlement program only if they had signed with a lawyer by June 11, 2026 and are otherwise eligible. Others proceed as regular lawsuits, with strict 90-day deadlines to produce records and expert reports. Each state also sets its own filing deadline. A participating firm can tell you where a new claim would stand.
Do not stop because of this page. Depo-Provera is contraception, and if you miss an injection you can become pregnant. Talk to the clinic or doctor who gives you the shot about your options. The new U.S. label, approved in December 2025, tells doctors to stop the drug if a meningioma is diagnosed.
In the news
Plain-English articles from our editorial team on the latest rulings, trials and deadlines, and what each one means if you are thinking about a claim.
Official resources
