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Cases pending in MDL 3140
as of July 2026
New cases filed in June alone
— a record month
Meningioma risk with prolonged
use, 2024 BMJ study
Upfront cost to have
your case reviewed
These claims are about one specific injury: a meningioma diagnosed after repeated Depo-Provera injections.
Meeting these guidelines does not mean you have a valid claim. It means a participating law firm is likely to review it. That firm decides on its own whether to take your case. Some claims are turned down, and some recover nothing. Direct2Attorney cannot judge the legal merits of your case, give legal advice, or file anything for you.
Most women do. Nobody reads the vial. Clinic and pharmacy records show what you were given and when, and a firm can pull them for you.
— Educational
Depo-Provera is contraception. If you miss an injection, you can become pregnant. Stopping without a plan is a real risk, and nothing here is medical advice.
If this page worries you, call the clinic or doctor who gives you the shot and ask about your options. There are other methods, and they can help you switch safely. That is a medical conversation, and it has nothing to do with any legal question.
Depo-Provera is an injection of medroxyprogesterone acetate. One shot every twelve weeks prevents pregnancy. For millions of women, it has been the simplest option available — nothing daily to remember, nothing to hide, nothing to explain.
A meningioma is a tumor that grows in the membranes covering the brain and spinal cord. Most are not cancerous. That does not make them harmless. As one grows, it presses on the brain, and treatment often means brain surgery.
Meningiomas carry hormone receptors. That is why researchers looked at long-term hormone injections in the first place.
In 2024 a large French study in the BMJ reported the finding at the heart of these cases. Women using medroxyprogesterone for a year or more had roughly 5.5 times the risk of needing surgery for an intracranial meningioma. A 2025 study in JAMA Neurology also found an increased risk, at a lower figure of about 2.4 times.
For years the U.S. label carried no meningioma warning at all. Labels in several other countries did. Women in the United States were not given the same information.
In December 2025 the FDA approved a new U.S. label warning of meningioma risk, telling doctors to monitor patients and to stop the drug if a meningioma is diagnosed. Anyone treated before then had no warning.
Pfizer argues federal preemption — that it asked the FDA to add a meningioma warning in 2024, the FDA refused, and it therefore cannot be blamed for a warning it was not permitted to give.
Plaintiffs argue the company knew far earlier and should have acted sooner. The court has not ruled on this. A ruling for Pfizer could sharply narrow the litigation.
Federal cases are consolidated as MDL 3140 before Judge M. Casey Rodgers in the Northern District of Florida, with 5,830 cases pending as of July 2026. On June 15, 2026, the court confirmed that Pfizer and plaintiffs’ leadership had reached a global agreement in principle giving eligible plaintiffs with pending MDL cases a chance to resolve their claims.
The financial terms have not been disclosed. The eligibility rules, the amount, and the claims process are all still being worked out, and none of it has been published. No court has approved any payment to anyone. The judge has vacated the December 2026 trial deadlines while the parties work it out.
This agreement arrived before any ruling on Pfizer’s preemption motion, before the causation ruling, and before a single trial. That is rare. It suggests both sides preferred certainty to the risk of those rulings. It also means nothing has been tested in court, and the deal is not yet binding on anyone.
Filings surged alongside it — 1,739 new cases in June, the largest single month in this MDL’s history. Cases in state court, mostly in New York and Delaware, are not part of the agreement.
The agreement covers eligible plaintiffs with cases already pending, and the eligibility criteria have not been published. Whether someone filing today would be included is not yet clear. Some firms have stopped accepting new Depo claims. Others are still reviewing them. Anyone who tells you a new claim is guaranteed a place in this settlement is guessing. A firm should give you a straight answer about where a new case would stand, and that answer costs nothing.
Meningiomas grow slowly, and the signs are easy to explain away. Headaches that get worse over months or are worst in the morning. Blurred vision or losing the edges of your sight. Hearing loss or ringing. Seizures. Weakness in an arm or leg. Memory problems or changes in personality that others notice before you do. If you have had the Depo shot for years and any of this sounds familiar, see a doctor and say so. Many meningiomas are found by chance on a scan done for something else. This page is general information, not medical advice.
— Compensation
If a claim succeeds, compensation is meant to cover what a brain tumor has cost you — the treatment, the time, and what did not come back afterward.
— The process
You do not need records, addresses or dates ready to start. Tell us what you remember and the firm does the rest.
Fill out the short form or call. Roughly how many years you had the shot, and when you were diagnosed. Two minutes, no cost, no obligation.
Because a settlement is being negotiated, a participating firm should tell you plainly where a new claim would stand. If your case would sit outside the agreement, you should hear that before you decide anything.
You sign an authorization. The firm requests clinic and pharmacy records showing the injections, plus imaging, pathology and surgical records for the tumor.
Your case is filed in the MDL or an appropriate state court. Your firm keeps you updated as the settlement terms are finalized. You are never required to accept an offer you do not want.
— Why people use us
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Contraception and medical history are personal. Your information is encrypted and handled according to our Privacy Policy.
What Direct2Attorney is
A legal marketing and referral service. We check whether your situation matches what participating law firms are looking for, and connect you with one of them if it does.
What Direct2Attorney is not
We are not a law firm. We cannot give you legal advice, represent you, or file anything on your behalf. Only a law firm you sign with can do that.
— Next step
A mass tort claim generally requires that you used a specific product, took a specific drug, or were exposed to a specific substance named in the litigation, and were later diagnosed with a condition that research or the litigation links to that exposure, within the relevant time window.
No. A free case review is free to you. Participating law firms handling mass torts typically work on a contingency basis, meaning legal fees are generally paid only if there is a recovery. Ask the firm to confirm its fee terms in writing.
Filing deadlines (statutes of limitations) vary by state and by litigation, and they can be shorter than people expect. That is why timing is one of the first things a participating firm checks — it is best not to wait to start a review.
Mass tort cases are grouped for efficiency because many people were harmed by the same product or exposure, but each person keeps an individual claim and an individual compensation outcome, unlike a class action.
It helps to have any medical records, prescriptions, diagnosis dates, receipts, or employment history that show your use, exposure, and diagnosis, though you do not need everything gathered before starting a free review.
A mass tort claim generally requires that you used a specific product, took a specific drug, or were exposed to a specific substance named in the litigation, and were later diagnosed with a condition that research or the litigation links to that exposure, within the relevant time window.
Ask it on the call. The review is free, and there is no obligation to move forward.
— News & updates

Women are suing over Depo Provera, claiming long-term use caused brain tumors like meningiomas. If you developed neurological symptoms, you

In 2025, Depo Provera lawsuits entered a new phase as regulators, medical researchers, and women’s health advocates pushed for deeper

Depo-Provera lawsuits in 2025 are helping women diagnosed with meningioma brain tumors seek justice. Learn your legal options and how